CFS PES Series Pharmaceutical Grade PES Pleated Filter Cartridges
(331) 215-4119
Custom Filtration Solutions PES Series polyethersulfone (PES) pleated filter cartridges provide highly efficient micronic and submicronic retention of particulates and microbial bio-burden in the production of pharmaceutical and biotechnology fluids. The highly asymmetric PES membrane offers excellent permeability and contaminant capacity. Excellent microbial retention with proven high LRV performance. The hydrophilic membrane allows for fast and easy wetting in aqueous fluids. Cartridges receive a thorough ultrapure water rinse to assure product cleanliness. Cartridges are 100% integrity tested to assure optimized retention performance.
Features
- Durable sequentially-layered PES and polypropylene components.
- Extreme porosity highly asymmetric membrane.
- Excellent fluid compatibility.
- UPW rinse assures low extractables.
Applications
- Large volume parenterals (LVPs)
- Small volume parenterals (SVPs)
- Active pharmaceutical ingredients (APIs)
- Ophthalmic solutions
- Biologicals: vaccine & blood products
- Buffers & reagents
Product Quality
- Individual elements are identified by serial number.
- Produced in a clean-room environment for product purity & cleanliness.
- Manufactured within an ISO 9001:2015 certified quality management system.
- Each element is integrity tested by diffusion flow.
- A Certificate of Quality document is provided with each production lot.
Microbial Retention Performance
| Rating | Microbial Retention |
| 0.2μm | Brevundimonas diminuta (ATCC 19746), ＞7 LRV |
| 0.45μm | Serratia marcescens (ATCC 14756), ＞6 LRV |
| 0.65μm | Saccharomyces cerevisiae, ＞5 LRV |
Materials of Construction
| Media: | Polyethersulfone |
| Support Layers: | Polypropylene |
| Cage/Core/End Caps: | Polypropylene |
| Adapter Reinforcement: | Polysulfone or Stainless Steel |
| Seal Options: | Silicone, NBR, EPDM, FKM, E-FKM |
Dimensions
| Diameter: | 69mm (2.72") |
| Lengths: | 10”, 20”, 30”, 40” |
Operating Conditions
| Operating Temperature: | 80°C (176°F) max. |
| Operating dP (max.): | 4 bar (58 psi) @ 20°C (68°F),2 bar (29 psi) @ 80°C (176°F) |
| Change-Out dP: | 2.6 bar (38 psi) @ 20°C (68°F) |
| Sterilization Recommendations | |
| Autoclave | 125°C (257°F), 30 minutes, 30 cycles |
| Steam-in-Place (SIP): | 125°C (257°F), 30 minutes, 30 cycles |
| Extractables, typical | |
| Per 10” element: | ﹤25mg non-dissolved solids |
Clean Pressure Drop
Effluent Quality
- Non-fiber releasing
- High LRV performance for effluent with increased microbial stability to prevent spoilage.
- Non-pyrogenic per USP Bacterial Endotoxin Requirements (>0.25EU/mL)
- Effluent meets USP Purified Water requirements for TOC, pH, and water conductivity
Write a Review
CFS PES Series Pharmaceutical Grade PES Pleated Filter Cartridges
